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CHEK2-Associated Li-Fraumeni-Like Syndrome

MedGen UID:: 322930
•Concept ID:: C1836482
•: Disease or Syndrome

Synonym:

Li-Fraumeni Syndrome 2

Definition

An autosomal dominant cancer predisposition syndrome caused by germline mutations of the CHEK2 gene. It is associated with breast carcinoma, gastric carcinoma, colorectal carcinoma, thyroid gland carcinoma, kidney carcinoma, prostate carcinoma, and non-Hodgkin lymphoma. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCHEK2-Associated Li-Fraumeni-Like Syndrome

Disease with Cushing syndrome as a major feature
- Li-Fraumeni syndrome
  - CHEK2-Associated Li-Fraumeni-Like Syndrome

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CHEK2-Associated Li-Fraumeni-Like Syndrome
CHEK2-Associated Li-Fraumeni-Like Syndrome

MedGen
C1836482[conceptid] (1)
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